Bacterial metabolite enhances immune checkpoint therapy against lung cancer
UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response…
Polyamines reshape protein phosphorylation to guide key cellular fate decisions
Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an…
Rare immune events link Epstein Barr virus to early multiple sclerosis damage
Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself. Yet for…
Study reveals genetic signatures linked to HIV-related cognitive impairment
Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV…
Preclinical study reveals potential new treatment for severe liver fibrosis
Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis – a dangerous, disease-induced build-up of…
Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial
A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a…
Single-cell analysis reveals gene disruptions in early-onset Alzheimer’s brain regions
A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell…
Key protein in the tuberculosis bacterium helps protect itself from foreign DNA
Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), have…
Durvalumab extends survival in small cell lung cancer but raises cost concerns
A new study suggests that the immune checkpoint inhibitor, durvalumab, may offer new treatment options for patients living…
Active mechanical forces drive how bacteria switch swimming direction
Scientists have uncovered a new explanation for how swimming bacteria change direction, providing fresh insight into one of…
New method measures how effectively antibiotics kill bacteria
Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory…
Giant amoeba-infecting viruses offer new clues to the origin of eukaryotic life
The origin of life on Earth becomes even more fascinating and complex as we peer into the mysterious…