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Browsing Tag

Central Nervous System

28 posts
HHealth
Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice
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Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice

  • September 10, 2026
A mouse study traces how immune cells activated in the intestine migrate to the dura and persist at…
NNutrition
Psychobiotic Strategies for Managing Anxiety, Depression, and Schizophrenia: A Narrative Review. Image Credit: Lightspring / Shutterstock
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Probiotics for mental health? A new review finds promising signals and major gaps

  • August 28, 2026
Researchers map the probiotic strains and gut-brain pathways being investigated across anxiety, depression, bipolar disorder, and schizophrenia, revealing…
HHealth
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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Study reveals why diffuse midline glioma develops in brain midline regions

  • August 27, 2026
Scientists at St. Jude Children’s Research Hospital have shown that specific brain cells respond differently to the H3.3…
HHealth
Study highlights the emotional and social challenges of stroke recovery
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International task force outlines roadmap for precision stroke recovery

  • August 19, 2026
An international task force co-led by a Georgetown University stroke expert has outlined a bold new roadmap for…
HHealth
Early B cell response prevents Oropouche virus from reaching the brain
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Plasma exchange improves recovery in rare inflammatory nerve disease

  • July 23, 2026
Plasma exchange can help treat people with a rare inflammatory disease that can cause blindness, according to a…
HHealth
GLP-1 receptor activation linked to lower depression and bipolar disorder odds
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GLP-1 receptor activation linked to lower depression and bipolar disorder odds

  • July 15, 2026
Lifelong genetic differences associated with GLP-1 receptor activity point to possible mental health benefits beyond weight and glucose…
HHealth
Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration
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Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration

  • June 11, 2026
A major immune pathway once known for detecting DNA damage is now being linked to brain aging, glial…
SScience
A cross section of a mouse nose. Image credit: Datta Lab, Harvard Medical School.
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Researchers Create Detailed Map of Smell Receptors in Mouse Nose

  • May 8, 2026
By mapping millions of smell-sensing neurons in mice, scientists discovered precise striped patterns inside the nose, overturning decades-old…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
HHealth
Early B cell response prevents Oropouche virus from reaching the brain
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Aston University bioscientist receives £125,000 to investigate genetic reasons for neurodegeneration

  • April 15, 2026
Aston University bioscientist Dr John Reynolds has won a £125,000 Springboard grant from the Academy of Medical Sciences…
SScience
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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New 3D organoid model advances pediatric glioma research and treatment

  • April 10, 2026
A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor…
HHealth
Caregiver feeding elderly woman with soup in dining room.
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Gut microbiome changes improve memory in early cognitive decline

  • April 1, 2026
From Mediterranean diets to probiotics, scientists reveal how reshaping the gut microbiome could help protect brain function, while…
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