Study proposes genetic basis for autism’s strong sex bias
Autism has a significant and enduring sex bias, with roughly four boys diagnosed for every girl. For many…
NUS uncovers NuSAP’s role in centriole stability
Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside…
Study: Ancient Mating Preferences, Not Natural Selection, Helped Shape Human Genome
Prehistoric humans and Neanderthals didn’t just interbreed, they did so with a consistent sex bias, as male Neanderthals…
Embryonic reproductive cells reveal striking genomic architecture before development
Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first…
Data-driven modeling uncovers dynamic genome folding in three dimensions
Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures…
Scientists discover spindle’s self-repair mechanism for accurate cell division
Every second, millions of cells in your body divide in two. In the space of an hour, they…
Dual pathways found for centromere specification, ensuring accurate chromosome segregation
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Despite the immense amount of genetic material present in each cell, around three…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
Study uncovers new mechanism for chromosome congression during mitosis
A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered…
Novel 3D chromosome mapping method can reliably reveal hidden structural variants
Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method…
Frogs help Fred Hutch find the shape of small things
Molecules too few and far between for standard cryo-EM Cryo-EM suspends purified and concentrated molecules in a super…
Nuclear binding protein identified as key contributor to trisomy 21-related CHDs
Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in…