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Browsing Tag

Cytokine

17 posts
HHealth
Immune cells communicate across a continuous, bidirectional circuit between the CNS and periphery. Immune cells from across the body engage CNS tissues and, in turn, are shaped by signals returning from the brain. (Left) Under peripheral equilibrium, immune effectors mobilized from visceral organs, secondary lymphoid organs, hematopoietic tissues, and the peripheral nervous system (PNS) - including CD4+ and CD8+ T cells, B cells, monocytes (top 3 cell types), NK cells, dendritic cells, mast cells, neutrophils, and innate lymphoid cells (bottom cluster of cells) - engage the CNS in a homeostatic dialogue that supports neural cell health, plasticity, and repair, sustaining a protective environment. (Right) Age-associated dysfunction across the same peripheral compartments reshapes this circuit: altered immune effectors enter the CNS and contribute to shifting the local environment toward a degenerative state in which microglia adopt disease-associated programs, astrocytes become reactive, and neurons accumulate pathology. This model underscores how the same circuitry can yield protective or pathogenic outcomes and that neurodegeneration is downstream of dysfunctional brain-immune crosstalk. Study: Neurodegeneration as a dysregulation of neuroimmune crosstalk
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Disrupted brain-immune signaling may help drive neurodegeneration

  • August 24, 2026
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
HHealth
Study: CD4 CTLs in supercentenarians: Signs of adaptive expansion in healthy aging. Image Credit: Sean Pavone   / Shutterstock
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A striking immune cell pattern emerges around a person’s 100th birthday

  • August 24, 2026
Rare immune cells found at strikingly high levels in people who live beyond 110 reveal an unusual pattern…
HHealth
Peroxisomes identified as alternative heat producers in brown fat
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Mitochondrial DNA mutations link to cardiometabolic parameters in metabolic syndrome

  • July 14, 2026
Background and objectives Mitochondrial DNA (mtDNA) variability, especially heteroplasmy, is believed to affect cellular immunobiogenesis, particularly in monocytes…
HHealth
Lab-grown corticospinal neurons offer new models for ALS and spinal injuries
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Study offers insight into how long-term inflammation may contribute to cognitive decline

  • July 7, 2026
The King’s College London study, published in Nature Communications, offers insight into how long-term inflammation may contribute to…
TTechnology
Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment
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Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment

  • June 29, 2026
A new study suggests that clearing symptom-driving nasal viruses could calm allergic inflammation and open a fresh treatment…
SScience
Study identifies PTX-3 as potential marker for long COVID and tissue damage
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New biomarkers identify trauma patients at risk for chronic critical illness

  • June 25, 2026
New research, published in The Journal of Immunology, identified biomarkers of a distinct immune profile that could be…
HHealth
Chlorinated compounds from slime mold show strong antibacterial activity
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Antibiotic minocycline shows potential for treating panic disorder symptoms

  • April 30, 2026
A study supported by FAPESP shows that small doses of the antibiotic minocycline may help treat panic disorder.…
HHealth
Young couple relaxing and sweating in hot sauna wrapped in towel. Woman and man In Sauna. Interior of Finnish sauna, classic wooden steam room with hot steam. Russian bathroom. Relax in hot Bathhouse.
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A single sauna session boosts immune cells within minutes

  • April 17, 2026
New research reveals how a brief Finnish sauna session mobilizes immune defenses within minutes, offering fresh clues into…
SScience
New technology embeds unique genetic identifiers in engineered cells
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CIPHER-seq technology reveals how immune cells communicate during treatment

  • April 8, 2026
A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic…
HHealth
Bowls with tasty almonds on color background
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Can eating almonds reduce inflammation in obesity?

  • March 12, 2026
A six-week randomized trial shows that adding almonds to the daily diet of adults with obesity can improve…
HHealth
Review: Zinc: A metallic shield against cardiac inflammation. Image Credit: Cagkan Sayin / Shutterstock
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How zinc deficiency could worsen heart inflammation and what that means for patients

  • March 2, 2026
New research suggests that zinc does far more than support immunity, revealing intricate molecular switches that may influence…
HHealth
Study: Immune modulation in response to coffee intake: a pilot study. Image Credit: ZeiMomArt / Shutterstock
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Study reveals coffee triggers distinct cytokine responses compared with pure caffeine

  • February 19, 2026
A controlled human study reveals that coffee’s complex chemical matrix may shape immune responses differently than pure caffeine,…
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