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Browsing Tag

DNA methylation

21 posts
HHealth
Study: How epigenetic clocks tick: unpacking the black box by deciphering biological pathways and transcriptomic signatures of accelerated aging. Image Credit: Lightspring / Shutterstock
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Five epigenetic clocks reveal shared and distinct signals of aging

  • July 22, 2026
A large multi-omics study maps why epigenetic clocks capture different aspects of aging and shows how gene-expression scores…
HHealth
The distinction between CA and BA and the progression of epigenetic clocks through multiple generations. (A) Chronological age reflects a uniform measure of time, whereas biological age reflects cellular and physiological decline. (B) First-generation clocks (e.g., Horvath, Hannum) were trained to predict chronological age. Second-generation clocks (e.g., PhenoAge, GrimAge) focus on phenotypic health and mortality risk. Third-generation clocks (e.g., DunedinPACE) measure the current rate of biological aging. The next generation of clocks aims to measure organ-specific biological age. Image adapted from Figure 1 in Cheema, B. S. et al. Functional, molecular, and digital measurements of biological age. The Journal of Clinical Investigation. 2026;136(12):e205777. doi:10.1172/JCI205777. Licensed under CC BY 4.0.
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New biological age tools could reveal health risks before symptoms appear

  • June 18, 2026
From gait speed and DNA methylation to AI scans and clinical text, a major review maps how scientists…
HHealth
Long-read sequencing uncovers massive DNA elements shaping human oral microbiome
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Epigenetic research links genetics and environment to mental disorders

  • May 18, 2026
Mental disorders, such as obsessive-compulsive disorder (OCD) and bipolar disorder, can strongly affect daily life. They are usually…
HHealth
Study: Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure. Image Credit: Oleksii Synelnykov / Shutterstock
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Study links common herbicide to rising early-onset colorectal cancer risk

  • April 23, 2026
A Spanish study used epigenetic fingerprints to trace hidden exposure patterns and found that a widely used herbicide…
SScience
New screening method boosts efficiency and accuracy of CAST genome editing
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New study reveals CRISPR enzyme that responds to human DNA methylation

  • April 20, 2026
Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a…
NNutrition
Good Housekeeping
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A New Study Found This Daily Habit May Help Slow Aging

  • April 7, 2026
This article contains affiliate links; if you click such a link and make a purchase, we may earn…
HHealth
A multivitamin a day could slow biological ageing, especially for those on unhealthy diets
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A multivitamin a day could slow biological ageing, especially for those on unhealthy diets

  • March 14, 2026
Taking a daily multivitamin may slow down biological ageing, a study has suggested. Experts calculate that taking daily…
HHealth
Li et al. evaluated the two-year effect of daily multivitamin-multimineral supplements and cocoa extract (500 mg cocoa flavanols per day, including 80 mg epicatechin) on five DNA methylation measures of biological aging among 958 participants (482 women and 476 men) in the COSMOS study. Image credit: Ri Butov.
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New Research Links Daily Multivitamins to Slower Biological Aging

  • March 11, 2026
In a randomized clinical trial of older adults, researchers found that taking multivitamins for two years modestly slowed…
SScience
Rapid neuronal evolution linked to high prevalence of autism in humans
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Long-read whole genome sequencing uncovers new genetic variants linked to autism

  • March 10, 2026
Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder…
HHealth
Overweight boy at nutritionist
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Puberty reshapes DNA to worsen or reverse insulin resistance

  • March 3, 2026
A longitudinal study shows that puberty may reprogram children’s epigenetic profiles in ways that track worsening or improving…
HHealth
Genetics and environment distinctively shape the human immune cell epigenome
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How DNA and life experiences leave distinct marks on the human immune system

  • January 29, 2026
A high-resolution immune cell atlas reveals how inherited DNA and life-long environmental exposures leave separate epigenetic signatures that…
TTechnology
Study: SARS-CoV-2 altered mitochondrial DNA methylation in Indian COVID-19 patients. Image Credit: CI Photos / Shutterstock
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COVID-19 severity is linked to changes in mitochondrial DNA methylation

  • January 21, 2026
New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered…
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