PTGES3 emerges as key regulator of androgen receptor in prostate cancer
A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player…
Hijacking cellular machinery within cancer cells to promote antitumor immunity
Investigators from Mass General Brigham have developed a way to promote antitumor immunity by hijacking cellular machinery within…
How walnuts combat inflammation and oxidative stress in the body
From protecting brain cells to modulating immunity, walnut bioactives demonstrate remarkable antioxidant and anti-inflammatory potential; however, scientists caution…
45,000-Year-Old Crimean Neanderthal Reveals Long-Distance Connections across Eurasia
The Crimean Peninsula in Ukraine contains key Middle to Upper Paleolithic transitional archaeological sites, including the site of…
Dysfunction in chromosome-stabilizing protein identified as a cause of deadly illnesses
New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
Researchers uncover mechanism by which BRCA2-deficient tumors develop chemoresistance
One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become…
Novel 3D chromosome mapping method can reliably reveal hidden structural variants
Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method…
Hypoxia weakens the body’s infection defense by changing genetic material of neutrophils
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body’s…
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Researchers found that mothers who ate both peanuts and peanut butter during pregnancy had children with distinct DNA…
Frogs help Fred Hutch find the shape of small things
Molecules too few and far between for standard cryo-EM Cryo-EM suspends purified and concentrated molecules in a super…
Ancient DNA uncovers paratyphoid and relapsing fever among Napoleonic troops
Scientists from the Institut Pasteur have genetically analyzed the remains of former soldiers who retreated from Russia in…