Automated workflow speeds bacterial sample preparation for genetic sequencing
Biomedical engineers at Brown University have developed a fully automated workflow that simplifies and accelerates the preparation of…
Wistar scientists develop new bispecific T cell engager to target ovarian cancer
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
Scientists link genetic spelling mistakes to sudden cardiac death
Scientists have found that the ‘sudden’ cardiac death condition related to high profile deaths or major medical episodes…
New tumor organoids strengthen precision oncology research
Significant advances have been made in the development of patient-derived tumor “organoids” for preclinical research, in two new…
New ctDNA blood test improves personalized prostate cancer treatment
A noninvasive DNA blood test can identify metastatic castration-resistant prostate cancer (mCRPC) patients who are most likely to…
New portable strip test accurately detects mosquito-borne viruses
A research team has developed a multisite bridging-mediated lateral flow immunoassay (mbLFIA) that enables highly sensitive, portable detection…
Diet helps people lose weight regardless of genetic obesity risk
A six-month clinical trial found that people with a high genetic risk for obesity benefited just as much…
New approach enhances radiotherapy by disabling cancer’s DNA repair machinery
Cancer treatments like radiation and chemotherapy work by doing one main thing: shredding the DNA of cancer cells…
Mitochondrial DNA mutations link to cardiometabolic parameters in metabolic syndrome
Background and objectives Mitochondrial DNA (mtDNA) variability, especially heteroplasmy, is believed to affect cellular immunobiogenesis, particularly in monocytes…
Integrating gene signatures and multi omics improves liver cancer treatment
Hepatocellular carcinoma (HCC) remains highly fatal due to late diagnosis and scarce early biomarkers. Multi‑omics and liquid biopsy…
Genes follow a random switching principle, yet remain precise on average
Inside the cell nucleus, genes must be turned on and off with precision to regulate biological processes. The…
Engineered ribozyme repairs broken RNA to explain origins of life
In most modern cells, DNA stores the genetic blueprint, and relies on proteins to replicate, repair and build…