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Browsing Tag

down syndrome

4 posts
HHealth
a, Collection and processing of venous plasma and capillary DPS and DBS samples. For DPS and DBS sample collection, a finger prick was carried out by trained study personnel and a few drops of capillary blood were spotted onto DPS and DBS collection devices. DPS and DBS were collected via semi-automated spot collectors and incubated with analyte-specific extraction buffer in a 96-well filter plate. After incubation and centrifugation, the eluate was immediately measured using ultrasensitive immunoassays on the single molecule array platform. b–f, Participant numbers and collection device numbers per cohort: capillary p-tau217 (b), capillary GFAP (c), capillary NfL (d), DS cohort (e) and self-sampling cohort (f). Panel a created using BioRender.com.
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Finger-prick blood test shows promise for detecting Alzheimer’s disease biology

  • January 7, 2026
A simple finger-prick dried blood test accurately tracked Alzheimer’s-related brain changes in research settings, pointing to a future…
HHealth
HMGN1 gene linked to heart problems in people with Down syndrome
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Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

  • October 22, 2025
Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in…
HHealth
HMGN1 gene linked to heart problems in people with Down syndrome
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HMGN1 gene linked to heart problems in people with Down syndrome

  • October 22, 2025
Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that…
MMental health
Program provides mental health services to those who can’t express themselves well
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Program provides mental health services to those who can’t express themselves well

  • September 9, 2025
A program in Prince George’s County, Maryland, provides mental health services to those already facing big intellectual challenges.…
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