Unprecedented atlas explores mitochondria across the tree of life
The protein catalogue gives a dynamic picture of the mitochondria, beyond what was known from humans and yeast.…
GLP-1 drugs fail to help some people lose weight — scientists are on a quest for answers
Some people taking the new generation of obesity drugs lose one-quarter of their body weight.Credit: Peter Dazeley/Getty Most…
AI co-scientists are revolutionizing how research is done
Biochemist Anna Pertl typed in her question, pressed Enter and left for the night. The artificial-intelligence system that…
Researchers mine cobra toxins to uncover a membrane-disrupting antimicrobial peptide
A computational search of cobra cardiotoxins put 14 venom-inspired peptides through structural, antibacterial, and toxicity testing, providing a…
Review highlights solute carriers as targets for central nervous system disorders
Solute carriers (SLCs) are specialized transport proteins that control the movement of nutrients, ions and neurotransmitters across cell…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Arugula nanovesicles counteract diet-induced obesity and modulate gut inflammation and microbiota in vivo
Competing interests The authors declare no conflicts of interest, except for C.L. for the patent WO 2024/223549 A1,…
Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer
Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the publication of a collaborative…
In world first, Israeli scientists find active ingredient in Viagra may stop cancer spread
In a surprising discovery, Israeli researchers say they have uncovered the biological mechanism in which Viagra, a drug…
7 life-saving medical innovations that could redefine healthcare
Over the past few years, several innovations have crossed important milestones, moving from experimental concepts toward real-world patient…
OpenAI researcher Miles Wang in talks to launch AI drug discovery startup valued at $2B
Miles Wang, an OpenAI researcher whose work includes using AI to accelerate scientific and biological discovery, is leaving…