A yeast-derived genetic tool offers hope for mitochondrial disorders and cancer
Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division. In…
Engineered enzyme enables fast and accurate RNA synthesis
From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as…
Engineered enzyme makes amides from aldehydes
Amide bonds hold together proteins. They appear in a huge number of drug molecules. They’ve been “one…
Aging brains struggle to recycle synaptic proteins
As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren’t sure why. …
Health benefits and risks uncovered
A new review finds that while the carnivore diet may deliver short-term improvements, weak evidence and emerging risks…
ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research
Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept…
Scientists uncover new mechanism initiating gene transcription
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular…
Combination therapy improves cognition in Alzheimer’s models
In recent years, research into cannabis and its main psychoactive ingredient, Δ⁹-tetrahydrocannabinol (THC), has unearthed medical benefits including…
Brain-specific enzyme drives branching and extension of O-mannose glycans
Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of…
New AI-driven method enables precise design of highly efficient custom enzymes
Enzymes with specific functions are becoming increasingly important in industry, medicine and environmental protection. For example, they make…
Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme | Sci.News
A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how…
Study shows DHPS enzyme controls macrophage maturation across multiple organs
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…