Paternal sperm epigenetics may help explain early pregnancy loss
When a pregnancy ends early and unexplained, the search for answers usually begins with the mother. Lacey Luense,…
AI-powered blood test detects liver cancer across distinct populations
Researchers at the Johns Hopkins Kimmel Cancer Center validated an artificial intelligence (AI)-powered blood test that accurately detected liver cancer…
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing
Adapting prime editing for mammalian histone mutagenesis Mouse canonical histone H3 is encoded by nine H3.1 and three…
Study explains how leukemia creates inflammatory lung environments
Acute myeloid leukemia (AML) does more than infiltrate the lungs: it also transforms lung tissue to create an…
Study validates research models for tracking circular extra-chromosomal DNA
Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs…
Scientists say they may be closer than ever to reversing aging
In old age, the liver’s DNA packaging starts to come undone. That breakdown does not change the genetic…
Restoring ADAR2 enzyme reduces metastatic spread in osteosarcoma
Osteosarcoma is the most common primary bone cancer in children, adolescents, and young adults. Although chemotherapy and surgery…
Epigenetic research links genetics and environment to mental disorders
Mental disorders, such as obsessive-compulsive disorder (OCD) and bipolar disorder, can strongly affect daily life. They are usually…
Fred Hutch researchers receive Prostate Cancer Foundation Young Investigator Awards
Two researchers at Fred Hutch Cancer Center recently received Young Investigator Awards from the Prostate Cancer Foundation for…
A hidden inheritance could explain disease risks beyond DNA
When we think about genetic inheritance, we usually leap to DNA, the four-letter code containing the instructions for…
New Research Shows Vitamin B12 May Hold the Key to Healthy Aging
A new Cornell study suggests vitamin B12 plays a far broader role in human biology than previously understood,…
Penn engineers use AI to solve some of science’s most difficult math problems
A ripple tells you something happened, but not exactly what. That is the core problem behind a hard…