Structural and evolutionary features of red algal UV sex chromosomes | Genome Biology
To define the male and female haplotypes of the sex-determining locus in Gracilaria species, we leveraged male reference…
SpatPPI: a geometric deep learning model for predicting protein–protein interactions involving intrinsically disordered regions | Genome Biology
Data preparation In this section, we introduce the details of the datasets used in this study, including the…
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…
Fossil From 310 Million Years Ago Rewrites the Story of Fish Evolution
Life reconstruction of Platysomus, with open mouth showing toothplate on the floor of the mouth supported by gill…
Variable efficiency of nonsense-mediated mRNA decay across human tissues, tumors and individuals | Genome Biology
Individual-level quantification of NMD efficiency We quantified the individual-level NMD efficiency (iNMDeff) by utilizing matched RNA-seq and whole-exome…
This Bug Waves at You in the Forest. The Reason Surprised Scientists
Matador bug, Bitta alipes (former Anisoscelis alipes), a leaf-footed bug (family Coreidae) with impressive, large, colorful flags on…
Biologists Baffled by Never-Before-Seen Structure in a Tiny Organism
Scientists have identified a previously unknown tubular structure inside a symbiotic bacterium that lives within the Asian citrus…
Machine learning and statistical inference in microbial population genomics | Genome Biology
Blackwell GA, Hunt M, Malone KM, Lima L, Horesh G, Alako BTF, et al. Exploring bacterial diversity via…
Hybrid BAG-seq: DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples | Genome Biology
Experimental designSamples We obtained fresh tissue samples of primary tumors from five patients with uterine cancer (Additional file…
From a 20-Foot Poop Pile, Scientists Uncover the Secrets of Giant Sloths
Ancient sloths lived in trees, on mountains, in deserts, boreal forests, and open savannahs. These differences in habitat…
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar Reetz MT, Wu…
Scientists Discover New “Ghost” Species of Marsupial, Closely Related to the Kangaroo
Bettong illustration. Credit: Nellie Pease Scientists have discovered a new species of marsupial in Australia’s bushland, closely related…