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Browsing Tag

Functional genomics

5 posts
SScience
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
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Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes

  • January 7, 2026
Sebé-Pedrós, A. et al. The dynamic regulatory genome of capsaspora and the origin of animal multicellularity. Cell 165,…
GGenetics
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes
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From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes

  • October 16, 2025
Strain culture and DNA extraction We used a collection of S. cerevisiae isolates that were previously sequenced using…
BBusiness
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
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Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology

  • September 23, 2025
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar  Reetz MT, Wu…
GGenetics
Methods and applications of in vivo CRISPR screening
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Methods and applications of in vivo CRISPR screening

  • September 9, 2025
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68–74 (2015). Article  PubMed  Google…
GGenetics
Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression
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Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression

  • September 9, 2025
James, S. L. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354…
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