Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…
New spatial omics platform advances biomedical research in Spain
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location…
Defective fat cells drive metabolic disease in lipodystrophy
Many people may have a dim view of their fat tissue, yet scientists have come to recognize adipose…
Engineered enzyme enables fast and accurate RNA synthesis
From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as…
RNA micelles enable targeted chemotherapy without immune toxicity
A new study in mice hints at the potential to use tiny particles made with RNA molecules to…
Study elucidates key steps in the ubiquitin tagging of mutated huntingtin protein
Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future…
Immune scaffold predicts onset weeks early
A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before…
Bacteria repurpose viral injection systems to target diverse cells
New study shows how bacteria adapted a virus-derived injection system to recognize and attach to many different types…
Novel RNA molecule may influence patient survival in certain blood cancers
In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Texas A&M University Health…
Blood gene signals reveal Parkinson’s risk years before diagnosis
Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s diagnosis. Study: Longitudinal assessment of…
Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help…
Scientists uncover new mechanism initiating gene transcription
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular…