Blood gene signals reveal Parkinson’s risk years before diagnosis
Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s diagnosis. Study: Longitudinal assessment of…
How DNA and life experiences leave distinct marks on the human immune system
A high-resolution immune cell atlas reveals how inherited DNA and life-long environmental exposures leave separate epigenetic signatures that…
Study reveals genetic signatures linked to HIV-related cognitive impairment
Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV…
Single-cell analysis reveals gene disruptions in early-onset Alzheimer’s brain regions
A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell…
Restoring protein production in motor neuron axons
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein…
Experiencing acute genomic care: perspectives from parents in the neonatal and paediatric intensive care units towards rapid genomic sequencing
Kingsmore SF, Nofsinger R, Ellsworth K. Rapid genomic sequencing for genetic disease diagnosis and therapy in intensive care…
Scientists discover how stem cells navigate and repair brain damage after stroke
Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of…
External signals control oncolytic bacteria for precise cancer therapy delivery
Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune…
How Do Periodical Cicadas Know When To Emerge?
How do 17-year cicadas, which live underground as nymphs, track the passage of time so they all emerge…
Blocking a ‘gerozyme’ reverses cartilage loss in mice
An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in…
X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies | BMC Genomics
Lyon MF. Gene action in the X-chromosome of the mouse (Mus musculus L). Nature. 1961;190:372–3. Google Scholar Berletch…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…