Scientists identify the neuroblastoma cells that signal poor outcomes
Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children…
Advances in chemistry and delivery are taking oligonucleotide medicines beyond rare diseases
Decades of work on RNA targeting, chemical modification, and tissue-specific delivery are reshaping what programmable genetic medicines can…
MIT researchers develop noninvasive way to spot aging zombie cells
As we age, some of the cells in our body enter a state of senescence, in which they…
New MRI measure maps blood flow and cellular organization
Researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of…
Genetic discovery offers clues for repairing damaged neural connections
A new discovery by neuroscientists at Brown University’s Carney Institute for Brain Science challenges long-held beliefs in neurobiology…
Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Sprint exercise sends a very different molecular signal through the body
Just minutes of all-out sprint work produced a striking surge in circulating proteins and metabolites, revealing how exercise…
Molecular mapping reveals hidden cellular programs in heart transplant rejection
A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine…
Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation
Gupta R, Woo K, Yi JA. Epidemiology of end-stage kidney disease. Semin Vasc Surg. 2021;34:71–78. https://doi.org/10.1053/j.semvascsurg.2021.02.010 Article PubMed …
Chinese researchers map epigenetic control of congenital heart defects
The findings have direct implications for clinical practice and future research. For genetic screening, the study provides a…
Five epigenetic clocks reveal shared and distinct signals of aging
A large multi-omics study maps why epigenetic clocks capture different aspects of aging and shows how gene-expression scores…
Study reveals sex-based protein differences across lung cancer types
Biological sex factors into cancer in ways you might not expect. In lung cancer, a form called squamous…