Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust…
Study advances the possibility of age-based pancreatic cancer treatment
While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging…
PTGES3 emerges as key regulator of androgen receptor in prostate cancer
A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player…
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Researchers found that mothers who ate both peanuts and peanut butter during pregnancy had children with distinct DNA…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
Nuclear binding protein identified as key contributor to trisomy 21-related CHDs
Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in…
Torino Identifies mRNA Isoforms in Disease-Related Gene Expression
Credit: libre de droit / Getty Images Different variants of a gene, known as isoforms, can be transcribed…
Torino Identifies mRNA Isoforms in Disease-Related Gene Expression
Credit: libre de droit / Getty Images Different variants of a gene, known as isoforms, can be transcribed…
Forensic genetics in the omics era
Jeffreys, A. J., Wilson, V. & Thein, S. L. Individual-specific ‘fingerprints’ of human DNA. Nature 316, 76–79 (1985).…
The genetic influence of sex on gene expression for blood in pigs | BMC Genomics
Data summary We collected 386 blood samples with matched genotype and gene expression data from the PigGTEx project…
Largest study of African American brain tissue reveals key Alzheimer gene activity
The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry…