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Browsing Tag

gene expression

85 posts
HHealth
Study uncovers three-way relationships between gut fungi, genetics and disease risk
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Study reveals why women face higher autoimmune disease risks

  • May 8, 2026
Ahead of World Lupus Day on May 10, new research from the Garvan Institute of Medical Research and…
HHealth
Study shows DHPS enzyme controls macrophage maturation across multiple organs
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Cell swelling in macrophages may trigger stronger inflammatory immune responses

  • May 8, 2026
As part of the body’s first line of defense against foreign invaders, macrophages play an integral role in…
SScience
Gene Syntax Determines DNA Supercoiling and Modulates Gene Expression
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Gene Syntax Determines DNA Supercoiling and Modulates Gene Expression

  • May 5, 2026
Digital DNA molecule, structure. Concept binary code human genome. DNA molecule with modified genes, 3D illustration When synthetic…
SScience
How chromatin movement helps control gene expression | MIT News
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How chromatin movement helps control gene expression | MIT News

  • May 4, 2026
Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome.…
HHealth
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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Molecular map reveals how Down syndrome alters brain development

  • April 25, 2026
Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human…
SScience
Boosting PI31 to restore synaptic function and prevent neurodegeneration
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Epigenome proteins shape dynamic gene expression beyond simple on-off

  • April 22, 2026
A new study finds the proteins responsible for controlling which genes are expressed in a genome do more…
HHealth
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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High-resolution study maps molecular differences across six human cortical regions

  • April 17, 2026
A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
HHealth
Study: Artificial and natural non-nutritive sweeteners drive divergent gut and genetic responses across generations. Image Credit: Andrii Zastrozhnov / Shutterstock
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Parents’ intake of sugar substitutes may influence offspring gut biology, study finds

  • April 14, 2026
A new mouse study suggests that sweeteners consumed by parents may reshape gut bacteria, microbial metabolites, and metabolic…
HHealth
Study: Tobacco smoke but not e-cigarette vapor induces epithelial barrier disruption, inflammation, and DNA damage in human Calu-3 cells. Image Credit: Antonio Marca / Shutterstock
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Lab study shows cigarette smoke damaged lung cells more than e-cigarette vapor

  • April 13, 2026
A new laboratory study found that cigarette smoke sharply disrupted lung cell defenses, while e-cigarette vapor showed no…
SScience
Cancer cells found to use ketones as alternate fuel for growth
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Damon Runyon supports young scientists driving cancer research innovation

  • April 12, 2026
The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and…
HHealth
UIC researchers discover an important cellular mechanism that drives aging
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Pseudogene lncRNAs regulate cancer stem cell behavior and signaling

  • April 12, 2026
Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to…
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