Scientists discover how stem cells navigate and repair brain damage after stroke
Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of…
External signals control oncolytic bacteria for precise cancer therapy delivery
Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune…
How Do Periodical Cicadas Know When To Emerge?
How do 17-year cicadas, which live underground as nymphs, track the passage of time so they all emerge…
Blocking a ‘gerozyme’ reverses cartilage loss in mice
An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in…
X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies | BMC Genomics
Lyon MF. Gene action in the X-chromosome of the mouse (Mus musculus L). Nature. 1961;190:372–3. Google Scholar Berletch…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust…
Study advances the possibility of age-based pancreatic cancer treatment
While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging…
PTGES3 emerges as key regulator of androgen receptor in prostate cancer
A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player…
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Researchers found that mothers who ate both peanuts and peanut butter during pregnancy had children with distinct DNA…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
Nuclear binding protein identified as key contributor to trisomy 21-related CHDs
Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in…