New method isolates true transcription factor targets in tuberculosis bacteria
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.…
Scientists put forward a new theory of brain development
Your brain begins as a single cell. When all is said and done, it will house an incredibly…
Study: Ancient Mating Preferences, Not Natural Selection, Helped Shape Human Genome
Prehistoric humans and Neanderthals didn’t just interbreed, they did so with a consistent sex bias, as male Neanderthals…
ATP delivery fixes dysfunctional dopamine packaging in Parkinson’s neurons
A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons – and…
New structural insights pave way for hantavirus vaccines
Hantaviruses, transmitted from rodents to people, have a death rate approaching 40%. They’re found around the world, and…
Expanded Seq-Scope method boosts gene-mapping resolution within tissues
In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity…
Study maps how NF-κB regulates gene expression in cells
To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department…
NIH’s continued investment fuels TMJ pain research
Chronic pain is one of the most common health conditions worldwide. Back pain is the most frequently reported…
Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Neanderthal DNA loss tied to ancient interbreeding dynamics
The human genome is a rich, complex record of migration, encounters, and inheritance written over thousands of millennia.…
Research maps lysosomal proteins to study neurodegeneration
Stanford researchers constructed an atlas of the proteins found in the lysosome across different brain cell types, a…
New Pico C technology maps genome structure before activation
For decades, scientists viewed the genome of a newly fertilised egg as a structural ‘blank slate’ – a…