Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the…
Ancient proteins revived to inspire new antimicrobial treatments
University of Oregon biologists have resurrected prehistoric proteins up to 160 million years old that carry natural antimicrobial…
Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Disrupted brain-immune signaling may help drive neurodegeneration
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
Cryo-EM provides real-time glimpse of cellular machinery reading DNA inside living organisms
All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the…
Understanding how maternal age impacts offspring health across different species
In humans and many other animals, a mother’s age can affect the physical and behavioral characteristics of the…
Sprint exercise sends a very different molecular signal through the body
Just minutes of all-out sprint work produced a striking surge in circulating proteins and metabolites, revealing how exercise…
Three minutes of sprinting dramatically reshape molecular contents of the bloodstream
Three minutes of sprinting can do something that 90 minutes of moderate exercise apparently cannot: dramatically reshape the…
Astrocytes found to directly regulate memory consolidation during sleep
Research has shown that a good night’s sleep has many benefits, including memory consolidation. How sleep enables the…
Possible relationship between genetic polymorphisms and the risk of exercise addiction among Turkish elite athletes: an exploratory pilot study
The present exploratory pilot study investigated genetic variants potentially associated with EA among elite Turkish athletes using a…
Molecular mapping reveals hidden cellular programs in heart transplant rejection
A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine…
New gene signature predicts immunotherapy success for bone marrow cancers
A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical…