Discovery of smOOP RNAs reveals hidden rules of cellular phase separation
Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing…
Blocking a ‘gerozyme’ reverses cartilage loss in mice
An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in…
Breakthrough platform reveals the choreography of mammalian transcription
Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads…
Researchers discover new mutation hotspot in the human genome
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA…
New insights into ribosome collisions and stress response
LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell. Ribosomes, the protein factories of…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s
Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the…
CRISPR-edited fungus boosts protein production and cuts environmental impact
In a new study publishing November 19 in the Cell Press journal Trends in Biotechnology, researchers used a…
Innovative new tool helps understand how gut microbes interact to influence health
The gut microbiome is made up of trillions of microbes that play a vital role in keeping us…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Blocking mir-21 shows promise for slowing bladder cancer growth
Bladder cancer ranks among the ten most common types of cancer worldwide. The main treatment is bladder removal…
Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust…