Lab-grown corticospinal neurons offer new models for ALS and spinal injuries
Researchers have developed a way to grow a highly specialized subset of brain nerve cells that are involved…
How DNA and life experiences leave distinct marks on the human immune system
A high-resolution immune cell atlas reveals how inherited DNA and life-long environmental exposures leave separate epigenetic signatures that…
Genes Tie Gut Motility to Surprising Nutrient: Vitamin B1
Analyzing data from more than 268,000 people, researchers found that genes involved in thiamine (vitamin B1) metabolism play…
MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors
The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system. This finding…
Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme | Sci.News
A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how…
Brain cell precursors show constant myelin-making drive
In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells – one…
Cancer’s double-edged sword of growth and DNA damage
New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers…
Bacteria behind Nagashima-type palmoplantar keratosis foot odor identified
The distinct foot odor that comes with the skin disorder Nagashima-type palmoplantar keratosis (NPPK) is caused by the…
COVID-19 severity is linked to changes in mitochondrial DNA methylation
New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered…
Using AI to understand the age of disease onset in Huntington’s patients
A team from the Faculty of Medicine and Health Sciences and the Institute of Neurosciences at the University…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
CTDNEP1 identified as potential tumor suppressor in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining…