COVID-19 severity is linked to changes in mitochondrial DNA methylation
New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered…
Using AI to understand the age of disease onset in Huntington’s patients
A team from the Faculty of Medicine and Health Sciences and the Institute of Neurosciences at the University…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
CTDNEP1 identified as potential tumor suppressor in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining…
Thermogenic beige fat protects blood vessels from hypertension
Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease is the leading cause of death worldwide. While…
Study reveals genetic signatures linked to HIV-related cognitive impairment
Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV…
Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial
A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a…
Single-cell analysis reveals gene disruptions in early-onset Alzheimer’s brain regions
A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell…
Fruit fly study identifies genes regulating dopamine and sleep
Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to…
DNA analysis of colorectal polyps improves diagnosis and treatment
In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.…
Restoring protein production in motor neuron axons
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein…
Scientists discover how stem cells navigate and repair brain damage after stroke
Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of…