New method reveals hidden protein motions for improved drug design
For many of us “protein” is the key element of a food order. However, beyond your preferred choice…
Genetic study maps bacteria’s protective armor behind severe infections
The first large-scale genetic study of E. coli’s protective armor has identified the five capsule types that are…
Palmatine improved fatty liver markers in a preclinical type 2 diabetes study
A new preclinical study suggests that palmatine may ease diabetes-linked fatty liver disease by targeting inflammation, oxidative stress,…
Lab-grown food pipe offers hope for children with esophageal conditions
Scientists from Great Ormond Street Hospital (GOSH) and University College London (UCL) have created the first lab‑grown esophagus…
Study finds addiction risk tied to reward and impulse genes
Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how…
New compound targets the neuronal epigenome to treat Alzheimer’s disease
A team from the University of Barcelona has designed and validated in animal models an innovative compound with…
Targeting protein fragment may improve Huntington disease treatments
Treatments that target a fragment of the mutant protein that causes Huntington’s disease might be more effective than…
Key gene mutation disrupts the brain’s ability to update beliefs in schizophrenia patients
One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients…
Modified lipid nanoparticles boost mRNA vaccines while reducing side effects
The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever…
Scientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteria
A novel engineered microbial system transforms discarded plastic into a frontline Parkinson’s treatment, offering a glimpse into a…
Study reveals dual role of PFK enzyme in metabolism and cell cycle progression
A metabolic enzyme studied for over seven decades has a hidden second function – it can unwind RNA…
Genomic sequencing may expand newborn screening beyond biochemical tests
Routine newborn screening (NBS) has transformed early disease detection. However, traditional biochemical tests limit the range of conditions…