Timing of genetic mutation dictates childhood leukemia aggressiveness
A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with…
Urine cfDNA patterns emerge as a promising tool for diagnosing bladder cancer
Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can…
Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis
Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting…
New analysis reveals fundamental flaws in widely used measures of biological aging
A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and…
AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
Epigenetic drift explains why the aging intestine becomes more vulnerable to cancer
Researchers from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, Germany, the Molecular Biotechnology…
Study sheds light on how extracellular vesicles mediate intercellular communication
A new study describes a key molecular mechanism that explains how cells exchange information through extracellular vesicles (EVs),…
Blocking a ‘gerozyme’ reverses cartilage loss in mice
An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in…
Uncovering the hidden metabolic effects of soybean oil
Soybean oil, the most widely consumed cooking oil in the United States and a staple of processed foods,…
Researchers discover new mutation hotspot in the human genome
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
CRISPR-edited fungus boosts protein production and cuts environmental impact
In a new study publishing November 19 in the Cell Press journal Trends in Biotechnology, researchers used a…