Changes in brain fats play a key role in Alzheimer’s development and progression
More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as “lipoid…
Study uncovers promising therapeutic strategies against neuroendocrine prostate cancer
A new study has uncovered promising therapeutic strategies against one of the deadliest forms of prostate cancer. McGill…
Blood group A linked to a higher risk of primary biliary cholangitis
A major retrospective study shows that people with blood group A face a higher likelihood of autoimmune liver…
Blocking mir-21 shows promise for slowing bladder cancer growth
Bladder cancer ranks among the ten most common types of cancer worldwide. The main treatment is bladder removal…
Researchers develop novel computational method to interpret complex single-cell data
Researchers from Turku Bioscience Centre at the University of Turku, Finland, have developed a new computational method to…
Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust…
Scientists map the genetic control system behind FOXP3 in immune cells
The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer,…
Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…
TAU researchers develop groundbreaking gene therapy to treat hearing, balance disabilities
“These findings highlight the potential of self-complementary AAVs to reduce dose requirements, minimize toxicity, and broaden clinical use…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
Researchers refine tools to map DNA’s 3D structure inside cells
DNA isn’t just a long string of genetic code, but an intricate 3D structure folded inside each cell.…