Chronic interferon exposure drives immunosuppression in tumors
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most…
Blood protein profiling could improve rare disease diagnosis
Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England…
New base editing techniques accurately modify genes in human embryos
A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques…
Weakened form of Mpox drove the 2022 global outbreak
The strain of Mpox behind the 2022 outbreak was a weakened form of the virus, which may have…
New approach repairs airway barrier defects in cystic fibrosis
A UNIGE team has succeeded in restoring the defective respiratory protective barrier in people with this rare genetic…
Autoimmune diseases form distinct genetic clusters, study finds
Different autoimmune diseases often share genetic risk factors, but not through a single common genetic vulnerability. In a…
Semaglutide extended lifespan in older female mice, but that was not the only finding
A late-life experiment reveals how a widely used metabolic drug reshapes age-related physiology and molecular pathways, with effects…
Early-onset bowel cancer shows distinct biological and clinical features
One of Australia’s largest real world studies of younger adults with advanced bowel cancer has identified important differences…
Study shows how cancer can act as a systemic disease
In their quest to understand how cancers take root, grow and spread, scientists have for the past half-century…
Why living to 100 may depend on far more than diet and exercise
From diet and exercise to social ties and genetics, researchers examined why the habits linked to healthier aging…
Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the…
New platform enables large-scale production of custom proteins
Scientists have been hard at work for more than 20 years to instruct biological systems, such as E.…