Antisense oligonucleotides reverse rare neurodevelopmental disorder in preclinical models
Scientists at St. Jude Children’s Research Hospital have found they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using…
Study reveals genetic factors influencing SYNGAP1 encephalopathy disease severity
SYNGAP1 encephalopathy is a rare genetic disorder for which there is no treatment, causing epilepsy, intellectual disability, psychomotor…
Calcium signals in microglia drive anxiety and compulsive behaviors
Researchers had previously discovered a population of immune cells within the brain that can act as accelerators and…
New method predicts cancer patient survival using advanced molecular data
Oregon Health & Science University researchers have developed a first-of-its-kind method to predict cancer patient survival using advanced molecular data from individual…
New mechanism disables antibiotic resistance and cross-protection in bacteria
A newly discovered mechanism renders antibiotic-resistant bacteria vulnerable by disabling both their individual resistance and a process known…
Early genomic testing prevents years of inconclusive visits for pediatric patients
For many families, eight years of uncertainty meant repeated specialist visits, inconclusive genetic tests and the growing fear…
APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…
Gut microbiome analysis may help detect Parkinson’s before symptoms appear
Analysis of microbes in the gut can reveal whether a person faces an elevated risk of Parkinson’s disease,…
Proteomics and AI bring earlier risk prediction into sharper focus
From Alzheimer’s risk to cardiovascular prediction, this review shows how protein profiling and AI could help detect disease…
How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
Migraine genes linked to worse headaches after concussion in children
A University of Calgary-led study has found evidence that children with genes predisposing to migraine might have an…
Aston University bioscientist receives £125,000 to investigate genetic reasons for neurodegeneration
Aston University bioscientist Dr John Reynolds has won a £125,000 Springboard grant from the Academy of Medical Sciences…