Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
Researchers uncover a chain of molecular events behind early brain changes in Alzheimer’s
For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer’s…
Study identifies a common hidden genetic cause of neurodevelopmental disorder in children
A major genetic study has uncovered a surprisingly common recessive cause of neurodevelopmental disorder, revealing how hidden changes…
AEGIS tool helps scientists study evolution of aging and lifespan
Why do some species live for only weeks while others survive for centuries? Researchers at the Leibniz Institute…
New brain circuit discovery offers hope for chronic pain treatment
A new map of a brain circuit specific to chronic pain suggests a promising route to treatment for…
A new global collaboration to expand patient-derived stem cell models and accelerate treatments
A new global initiative launched today aims to close a critical gap in ALS/MND drug discovery – current…
How could bisphenol A raise depression risk? Study identifies six key molecular targets
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…
Study proposes genetic basis for autism’s strong sex bias
Autism has a significant and enduring sex bias, with roughly four boys diagnosed for every girl. For many…
Modern lifestyle amplifies genetic risk for type 2 diabetes
Some people have a greater genetic risk than others of developing type 2 diabetes. Now, more of these…
Study opens the door for future treatments for Sleeping Sickness
To survive in the human bloodstream, the African trypanosome parasite wears a “cloak” made of proteins known as…
CFHR1 could be a new diagnostic marker for IgA nephropathy
Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs)…
New neural organoid system improves scalability and reproducibility for research
Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields. These include exploring the responses of brain tissue to drugs,…