Study reveals poxvirus’s unique DNA clamp for gene activation
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study…
A yeast-derived genetic tool offers hope for mitochondrial disorders and cancer
Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division. In…
Study explores whether a bidirectional causal link exists between MASLD and sarcopenia
Background and aims Metabolic dysfunction-associated steatotic liver disease (MASLD) and sarcopenia frequently coexist, yet their causal relationship and…
Genetic variants in 11 regions of human genome influence the gut microbiome
In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions…
Rising lung cancer in never smokers demands urgent research focus
Lung cancer patients who have never smoked make up a significant and growing share of global lung cancer…
Study reveals insights into how cells coordinate gene compensation response
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or…
Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…
Defective fat cells drive metabolic disease in lipodystrophy
Many people may have a dim view of their fat tissue, yet scientists have come to recognize adipose…
Mesothelial cells enable rapid invasion and spread of ovarian cancer
Ovarian cancer kills more women than any other gynecological cancer. Most patients receive their diagnosis only after the…
Study elucidates key steps in the ubiquitin tagging of mutated huntingtin protein
Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future…
Research shows the effect of losing weight in preventing multiple diseases
Researchers have quantified the role of obesity in common long-term conditions, showing for the first time the effect of losing weight in preventing multiple diseases. …
Novel RNA molecule may influence patient survival in certain blood cancers
In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Texas A&M University Health…