AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Gene variant linked to higher risk of chronic rejection after lung transplant
About one third of lung transplant recipients have a genetic variant that makes them more likely to develop…
The future of cancer detection could be just a blood test away, say scientists
The prospect of diagnosing cancer through painless methods—such as a simple AI-assisted blood or urine test that detects…
Rising complexity in pediatric hospitalizations highlights urgent workforce and policy needs
A new national analysis shows that over the past two decades, inpatient care for children with complex chronic…
Breakthrough platform reveals the choreography of mammalian transcription
Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
These archaea built a distinct genetic code to put pyrrolysine in proteins
 There are few hard and fast rules in the study of life, but perhaps the closest we…
New insights into ribosome collisions and stress response
LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell. Ribosomes, the protein factories of…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Landmark prostate cancer screening trial launches in the UK
The first men have been invited to take part in Prostate Cancer UK’s TRANSFORM trial, kicking off the…
Young donor age proves critical for survival after stem cell transplantation
The selection of suitable donors is crucial for the long-term recovery of patients after an allogeneic hematopoietic stem…