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Browsing Tag

Genetics research

11 posts
TTechnology
Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation
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Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation

  • July 30, 2026
Gupta R, Woo K, Yi JA. Epidemiology of end-stage kidney disease. Semin Vasc Surg. 2021;34:71–78. https://doi.org/10.1053/j.semvascsurg.2021.02.010 Article  PubMed …
HHealthcare
Genomas Brasil program: building precision public health within Brazil’s Unified Health System
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Genomas Brasil program: building precision public health within Brazil’s Unified Health System

  • July 21, 2026
Patel, H. N. et al. J. Pharm. Bioallied Sci. 17, S1101–S3 (2025). Article  PubMed  PubMed Central  Google Scholar …
HHealth
A multi-dimensional framework for establishing and managing a genomic newborn screening program
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A multi-dimensional framework for establishing and managing a genomic newborn screening program

  • February 28, 2026
The above-described methodology resulted in a multi-dimensional framework for a gNBS program consisting of 18 screening criteria (Table 1)…
HHealthcare
Florida law models what genetic disease testing could be
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Florida law models what genetic disease testing could be

  • February 10, 2026
In Florida, a new genetic disease screening program allows parents of newborns to receive free whole genome sequencing…
GGenetics
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
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Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers

  • October 17, 2025
Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…
GGenetics
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
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Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

  • October 11, 2025
Ethics Our research complies with all relevant ethical regulations. All studies included in this research were approved by…
GGenetics
The Solve-RD Solvathons as a pan-European interdisciplinary collaboration to diagnose patients with rare disease
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The Solve-RD Solvathons as a pan-European interdisciplinary collaboration to diagnose patients with rare disease

  • September 15, 2025
School of Computation, Information and Technology, Technical University of Munich, Garching, Germany Vicente A. Yépez, Rebeka Luknárová, Felix Brechtmann, Leon Kraß, Shubhankar…
GGenetics
Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs
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Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs

  • September 15, 2025
Identifying the structures of autism phenotypes To best reflect the complexity of presentations across autistic individuals, we identified…
GGenetics
Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling
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Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling

  • September 14, 2025
Fogg, C. et al. The dynamics of frailty development and progression in older adults in primary care in…
GGenetics
A genome-wide association analysis reveals new pathogenic pathways in gout
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A genome-wide association analysis reveals new pathogenic pathways in gout

  • September 11, 2025
Kuo, C. F. et al. Global epidemiology of gout: prevalence, incidence and risk factors. Nat. Rev. Rheumatol. 11,…
GGenetics
Whole-exome sequencing analysis identifies risk genes for schizophrenia
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Whole-exome sequencing analysis identifies risk genes for schizophrenia

  • September 9, 2025
Lally, J. & MacCabe, J. H. Antipsychotic medication in schizophrenia: a review. Br. Med. Bull. 114, 169–179 (2015).…
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