LNPs Powering the Future of Gene Editing & Therapy
Gene therapy has long promised to transform the treatment of genetic and acquired diseases by addressing the underlying…
Structural variation in 1,019 diverse humans based on long-read sequencing
Samples and DNA extraction We initially selected 1,064 samples from the 1kGP collection, sourcing genomic DNA from Coriell…
Stealth Genetic Switch in Mosquitoes Halts Malaria Spread
Genetically modified mosquito larvae express fluorescent markers of the FREP1 gene — RFP (pink), GFP (blue) or both…
Large-scale genome-wide analyses of stuttering
Yairi, E. & Ambrose, N. Epidemiology of stuttering: 21st century advances. J. Fluen. Disord. 38, 66–87 (2013). Article …
Methods and applications of in vivo CRISPR screening
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68–74 (2015). Article PubMed Google…
Japan expands preimplantation genetic testing eligibility
The Japan Society of Obstetrics and Gynecology on Monday began allowing infertile couples involving women who are 35…
Light Switches Give Scientists Control Over Cells
Imagine being able to flip a light switch to control disease pathways inside a living cell. A team…
Doctors say strokes in young adults congenital, advise early genetic screening
Always confident about his health, this man, who worked as a technician and whose name is not revealed,…
Whole-exome sequencing analysis identifies risk genes for schizophrenia
Lally, J. & MacCabe, J. H. Antipsychotic medication in schizophrenia: a review. Br. Med. Bull. 114, 169–179 (2015).…
World Athletics’ mandatory genetic test for women athletes is misguided. I should know – I discovered the relevant gene in 1990
World Athletics president Sebastian Coe recently announced a new rule for women athletes, requiring mandatory genetic tests to…
Bilingualism possible in people with rare genetic condition that normally limits speech
Rett syndrome is a rare neurological condition that disrupts physical and linguistic development, affecting around one in 10,000…
Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer
de Magalhaes, J. P. How ageing processes influence cancer. Nat. Rev. Cancer 13, 357–365 (2013). Article PubMed Google…