New diagnostic framework addresses challenges of rapidly-mutating RNA viruses
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex…
Data-driven modeling uncovers dynamic genome folding in three dimensions
Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures…
How DNA and life experiences leave distinct marks on the human immune system
A high-resolution immune cell atlas reveals how inherited DNA and life-long environmental exposures leave separate epigenetic signatures that…
Genes Tie Gut Motility to Surprising Nutrient: Vitamin B1
Analyzing data from more than 268,000 people, researchers found that genes involved in thiamine (vitamin B1) metabolism play…
Study traces deep origins of syphilis to prehistoric Americas
A newly sequenced genome of the bacterium that causes syphilis, Treponema pallidum, highlights the deep antiquity of treponemal diseases in…
Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme | Sci.News
A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how…
The Northern Finland Birth Cohort 1966 enters a new era of aging research
One of the world’s most extensive birth cohorts is now entering later adulthood. At the University of Oulu in…
Large study identifies more than 100 genetic regions linked to schizophrenia
A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate…
New genetic insights reveal vitamin B1’s role in gut health and motility
Bowel habits aren’t exactly dinner-table talk. But they reflect how quickly the gut moves things along, and when…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
Key protein in the tuberculosis bacterium helps protect itself from foreign DNA
Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), have…
Gut Microbes Played Role in Evolution of Human Brain, New Study Suggests
Compared to other primates, humans have remarkably large brains relative to their body sizes. The resultant high demands…