Genomic sequencing may expand newborn screening beyond biochemical tests
Routine newborn screening (NBS) has transformed early disease detection. However, traditional biochemical tests limit the range of conditions…
New review reveals complex polygenic architecture underlying common epilepsies
An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common…
AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes
Trained on genomic data spanning the tree of life, Evo 2 reveals how artificial intelligence can decode the…
New fragmentome technology can detect early liver fibrosis and cirrhosis
Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free…
New research on two million people quantifies how genetic risks overlap across diagnoses
A sweeping new peer-reviewed study published in Genomic Psychiatry has introduced a concept that could reshape how psychiatrists…
New method isolates true transcription factor targets in tuberculosis bacteria
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.…
Jumping DNA fragments found to destabilize cancer genome
A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite,…
Neanderthal DNA loss tied to ancient interbreeding dynamics
The human genome is a rich, complex record of migration, encounters, and inheritance written over thousands of millennia.…
New spatial omics platform advances biomedical research in Spain
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location…
Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help…
New diagnostic framework addresses challenges of rapidly-mutating RNA viruses
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex…
How DNA and life experiences leave distinct marks on the human immune system
A high-resolution immune cell atlas reveals how inherited DNA and life-long environmental exposures leave separate epigenetic signatures that…