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Browsing Tag

Glucagon

43 posts
TTechnology
Trial: Dapiglutide, a dual GLP-1 and GLP-2 receptor agonist, for obesity: a randomised, double-blind, placebo-controlled parallel-group, proof-of-concept trial. Image Credit: Alones / Shutterstock
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Combined GLP-1 and GLP-2 treatment appears safe but does not beat placebo for obesity

  • February 25, 2026
Can combining two gut hormone pathways unlock better obesity treatments? In the first human trial of dapiglutide, researchers…
HHealth
Central mechanisms by which peripheral GLP-1RAs may reduce appetite or induce nausea. Peripheral GLP-1 or GLP-1RAs may interact with appetite-regulating regions of the brain via gaps in the blood-brain barrier, via tanycyte uptake, or indirectly via the nodose ganglia. The effects to slow gastric emptying, induce nausea, and reduce energy intake are independent. AgRP, agouti-related peptide; AP, area postrema; ARC, arcuate nucleus; BBB, blood-brain barrier; CART, cocaine- and amphetamine-regulated transcript; H, hypothalamus; lPBN, lateral parabrachial nucleus; NAc, nucleus accumbens; NPY, neuropeptide Y; NTS, nucleus tractus solitarius; POMC, proopiomelanocortin; VTA, ventral tegmental area.
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How GLP-1 drugs affect the body beyond weight loss and glucose control

  • February 19, 2026
Widely used weight-loss and diabetes drugs show clear benefits, but emerging evidence clarifies their side effects, rare risks,…
HHealth
various types of fresh meat: pork, beef, turkey and chicken on a wooden table, top view
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Unprocessed beef does not worsen metabolic health in prediabetes

  • February 2, 2026
A controlled crossover trial finds that short-term consumption of unprocessed beef is on par with poultry for glucose…
HHealth
Improving survival in people with severe psychiatric disorders
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Improving survival in people with severe psychiatric disorders

  • January 26, 2026
An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap…
HHealth
Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk
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Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

  • December 15, 2025
Swapping common snack foods for a modest daily portion of tree nuts curbed cravings for sweets and fast…
HHealth
Peroxisomes identified as alternative heat producers in brown fat
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WHO releases first guideline on the use of GLP-1 therapies for treating obesity

  • December 2, 2025
To address the growing global health challenge of obesity, which affects more than 1 billion people, the World Health…
HHealth
Stopping GLP-1 drugs before pregnancy leads to more weight gain
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Stopping GLP-1 drugs before pregnancy leads to more weight gain

  • December 1, 2025
New research shows that women who halt GLP-1 medications near conception face greater gestational weight gain and elevated…
HHealth
Automated insulin delivery improves glucose control in pregnant women with Type 1 diabetes
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Regenerative medicine offers a pathway toward curing type 1 diabetes

  • November 26, 2025
Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells. While…
HHealth
Study: Interest in Facial Volume Restorative Procedures With the Rise in “Ozempic Face”: A Google Trends Analysis. Image Credit: Alones / Shutterstock
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Searches for “Ozempic face” surge as people look for filler-based solutions

  • November 21, 2025
New search data reveal that as interest in “Ozempic face” surges, people increasingly turn to nonsurgical fillers rather…
HHealth
Study: Efficacy and safety of glucagon-like peptide 1 receptor agonists across all health outcomes in type 2 diabetes: An umbrella review and evidence map of randomised controlled trials. Image Credit: zimmytws / Shutterstock
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Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

  • November 20, 2025
A new umbrella review reveals how GLP-1 therapies shape cardiovascular, renal, and metabolic outcomes in type 2 diabetes…
HHealth
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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Tirzepatide may only temporarily suppress brain activity involved in “food noise”

  • November 18, 2025
A rare glimpse into the brain activity of a patient with obesity and loss of control eating on…
HHealth
Perspective: The Uncharted Territory of the New Obesity Drugs in Users Without Obesity: A Sociomedical Perspective. Image Credit: Pietukhova / Shutterstock
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Off-label GLP-1 use highlights the cultural pressures driving body anxieties

  • November 14, 2025
A new sociomedical perspective shows how off-label use of GLP-1 drugs for slimness is redefining what counts as…
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