Targeting CMPK2-intervened redox metabolism to mitigate hepatic ischemia-reperfusion injury
HIRI is a major clinical challenge that occurs when blood supply to the liver is temporarily interrupted and…
Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles
Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during…
New Framework Aims to Transform High-Altitude Medicine Through Whole-Body Approach to Hypoxia
Figure 1. Conceptual framework of Hypoxia Stress-induced Multi-organ Injury (HSMI). Figure 2. Future directions for advancing high-altitude medicine…
Photodynamic strategies enhance antibacterial performance of titanium orthopedic implants
1. Background The increasing global aging population has led to a steady rise in the demand for titanium…
Tumor microenvironment drives resistance to ferroptosis in pancreatic cancer
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can…
Mild hypoxia in preterm infants linked to lifelong memory issues
During intensive care after preterm births, babies can experience low oxygen in their tissue and cells-or hypoxia. Hypoxia…
Novel microneedle patch accelerates healing of chronic diabetic wounds using light
Researchers from Nanjing Drum Tower Hospital, Southeast University, and Wenzhou Medical University have developed a novel microneedle patch…
Researchers show red blood cells drive better glucose tolerance at high altitude
New research reveals how hypoxia-driven red blood cell adaptations may reshape glucose regulation, offering fresh insight into diabetes…
Low oxygen turns red blood cells into powerful glucose sinks
Scientists have long known that people living at high altitudes, where oxygen levels are low, have lower rates…
Hypoxia rewires red blood cells to clear excess glucose
In a 2023 paper on hypoxia and glucose metabolism, our lab showed how organisms rewire their metabolism to…
How Do Athletes Train to Avoid Altitude Sickness?
Some athletes go to the gym. Some run long distances across vast terrains. Some even build their fitness…
Bradycardia emerges as key clinical sign of xylazine-opioid overdose
Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose. This breakthrough finding from the…