BCG vaccine may remodel the human brain’s immune environment
New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine – which is…
Engineered scaffold restores skull growth in craniosynostosis mouse models
An engineered triphasic biomaterial scaffold successfully recreated the cranial suture stem cell niche lost in craniosynostosis, a condition…
New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
Probiotic metabolite found to suppress melanoma tumor growth in mice
Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond…
Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment
A new study suggests that clearing symptom-driving nasal viruses could calm allergic inflammation and open a fresh treatment…
Donald Trump’s Gaza Board of Peace plans sweeping legal immunity framework
US President Donald Trump‘s Board of Peace (BoP) is planning to grant itself total legal immunity for actions…
US study shows updated COVID vaccines cut hospitalization odds by 55%
In an early-season US analysis of more than 111,000 medically attended illness encounters, updated COVID vaccines showed meaningful…
Fiber-derived butyrate may shape immune cell development, mouse study finds
Researchers reveal that butyrate promotes the development of dendritic cells, which they note are known as the “sentinels”…
Prime and pull vaccine approach prevents genital herpes infection
Genital herpes is a lifelong infection. While available treatments can manage symptoms, they cannot cure the infection or…
Synthetic gut communities reveal how diet rewires the microbiome
By simplifying the gut’s microbial complexity, synthetic communities could help scientists pinpoint how specific foods influence microbial function,…
Study highlights variable synbiotic relationship of prebiotics and probiotics
Adults with obesity who consumed a dietary fiber supplement had positive effects on high-density lipoprotein cholesterol (HDL-C) and…
Neutrophils reduce the effectiveness of cancer immunotherapy in mice
A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less…