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Browsing Tag

immunity

117 posts
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
HHealth
Scientists identify key protein driving severe flu in older people
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New flu vaccine approach targets multiple virus strains

  • April 15, 2026
Doctors recommend getting your flu shot annually, since the specific influenza strain it targets varies from year to year.…
HHealth
UC Riverside receives $2 million grant to explore how gut bacteria shape human health
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Social closeness drives the exchange of gut bacteria

  • April 10, 2026
Living with friends may quietly be altering your gut bacteria – according to a new study from the…
HHealth
New NIH grant supports development of experimental pediatric HIV vaccine
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Novel mucosal vaccine offers broad protection against diverse influenza viruses

  • April 4, 2026
A novel vaccine platform has been developed to induce broad, protective immunity against numerous influenza virus infections, showing…
HHealth
Affordable drug found to be effective in treating seriously ill COVID-19 patients
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Study revises the understanding of neutrophil dynamics during respiratory viral infection

  • March 24, 2026
Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these cells…
TTechnology
Cancer cells found to use ketones as alternate fuel for growth
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New insights highlight multifaceted roles of CD4+ T cells in tumor immunity

  • March 14, 2026
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
HHealth
Bowls with tasty almonds on color background
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Can eating almonds reduce inflammation in obesity?

  • March 12, 2026
A six-week randomized trial shows that adding almonds to the daily diet of adults with obesity can improve…
HHealth
NIH awards $3.4 million to support research on Crimean-Congo hemorrhagic fever virus
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Maternal antibodies protect newborns from severe E. coli infections, study finds

  • March 11, 2026
A multi-center study led by researchers at Cincinnati Children’s sheds surprising new light on why some newborns become…
TTechnology
DNA origami vaccine platform shows promise against multiple infectious viruses
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DNA origami vaccine platform shows promise against multiple infectious viruses

  • March 11, 2026
The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical…
HHealth
Study: Physical activity for public health in the 21st century. Image Credit: New Africa / Shutterstock
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Global study reveals how inequality limits access to exercise and why it matters for health

  • March 11, 2026
A global analysis shows that who gets the chance to exercise is shaped by wealth and gender, while…
HHealth
Study links brain waves to misremembering of negative, irrelevant information
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Sleep and diet emerge as key drivers of immunome variation

  • March 10, 2026
Immunome (immune cells and functions) variations are closely related to human health. Various exposures, including the external environment…
HHealthcare
Kansas City health officials confirm first measles case in eight years
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Kansas City health officials confirm first measles case in eight years

  • March 4, 2026
A Kansas City resident has tested positive for measles, marking the city’s first confirmed case in eight years.…
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