Neutrophils reduce the effectiveness of cancer immunotherapy in mice
A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less…
Popular supplement creatine supercharges critical immune cells fighting cancer
Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical…
In a world first, Israeli scientists find ‘memory’ B cells can target ovarian tumors
Researchers at the Weizmann Institute of Science announced Tuesday they have discovered, in a world first, that specialized…
Mitochondrial checkpoint enables dendritic cells to activate T lymphocytes against viruses, tumors
A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial “checkpoint”…
Scientists capture immune cells attacking live melanoma cells in real time
Scientists at the Garvan Institute of Medical Research have captured, for the first time, ‘housekeeping’ immune cells actively…
Experimental virus therapy targets resistant high-grade neuroendocrine tumors
A phase I clinical trial is testing whether a tumor-targeting virus can help immunotherapy work more effectively against…
New gene expression signature may guide immunotherapy for resistant prostate cancer patients
Researchers with the James P. Allison Institute™ at The University of Texas MD Anderson Cancer Center have discovered a…
Small T-cell subset drives powerful multiple myeloma immunotherapy responses
Researchers from The University of Osaka find that only a small fraction of T cells may drive the…
Polymer-based immunotherapies enhance tumor targeting and immune activation
Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less…
Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity
Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset…
Researchers uncover how bacterial toxin damages colon lining cells to trigger cancer
Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor…
Multi-center research initiative aims to improve glioblastoma patient outcomes
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center are part of a new multi-institution research effort aimed at improving…