Researchers uncover how bacterial toxin damages colon lining cells to trigger cancer
Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor…
Multi-center research initiative aims to improve glioblastoma patient outcomes
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center are part of a new multi-institution research effort aimed at improving…
A new combined therapy to boost the immune system against cancer
Cancer immunotherapy is built on a simple but powerful idea: the immune system can recognize and destroy cancer…
Non-invasive profiling of the tumour microenvironment with spatial ecotypes
Human subjects All human samples included in this study were collected with informed consent for research use and…
Tumor splicing burden predicts treatment response in kidney cancer
Researchers at City of Hope® and TGen (part of City of Hope) have identified a significant correlation between…
Tip Sheet: Improving outcomes for stem cell transplants, exploring the link between solar jetlag and liver cancer — and expanding cancer treatment targets
Is there a way to boost immunotherapy response?
Molecular biologist Kevin Barry, PhD, received a $270,000, two-year grant…
Food timing may shape how T cells respond to infection and therapy
A new study reveals how lipids released after a meal can durably boost T cell metabolism, translation, and…
Liquid biopsy predicts immune response in high-risk breast cancer patients
Immunotherapy has become a standard of care in treating high-risk, early-stage breast cancers, yet it has had limited…
New imaging method maps DNA replication forks with single-cell resolution
Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as…
Muscle energy recovery may explain fatigue in cancer survivors
Even apparently healthy cancer survivors often complain of extreme fatigue. They have finished treatment, the scans are clear,…
Targeting glutamine metabolism enhances CAR-macrophage cancer therapy
Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…
New biomarker predicts prognosis and treatment response in colorectal cancer
Determining the presence of a protein in non-tumor cells within the cancer microenvironment could be one of the keys to establishing prognosis…