Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Timing Is Everything In Cancer Immunotherapy, Experts Say | Health
Key Takeaways Cancer immunotherapies might work better if given earlier in the day Lung cancer patients had better…
Targeted approach of immunotherapy improves sepsis outcomes
Immunotherapy for sepsis is effective when doctors tailor the treatment precisely to the patient’s immune system condition. While…
Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL
A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic…
Neoantigens-loaded DC vaccines show strong potential to overcome tumor resistance
Despite the success of immune checkpoint inhibitors in revolutionizing oncology, their benefits remain limited to a small fraction…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…
Bowel cancer’s “Big Bang” moment reveals how the disease takes shape
Like the astronomical explosion that kickstarted the universe, bowel cancer has a “Big Bang” moment which determines how…
Hijacking cellular machinery within cancer cells to promote antitumor immunity
Investigators from Mass General Brigham have developed a way to promote antitumor immunity by hijacking cellular machinery within…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Advances in diagnosis and management of systemic light chain amyloidosis
Systemic light chain (AL) amyloidosis is a rare and life-threatening disorder characterized by the deposition of misfolded immunoglobulin…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…