Sprint exercise sends a very different molecular signal through the body
Just minutes of all-out sprint work produced a striking surge in circulating proteins and metabolites, revealing how exercise…
Microbial metabolites could help improve functional cure rates for hepatitis B
Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure…
Cigarette smoke extract primes airway cells for greater nanoplastic damage
A laboratory model reveals how smoke-damaged epithelial barriers may leave airway cells more vulnerable to a second environmental…
Occult hepatitis B mutations drive liver cancer growth via Akt mTOR pathway
Occult hepatitis B virus (OBI) infection presents a significant global health challenge, notoriously flying under the radar of…
Stem cell study uncovers molecular pathway for enamel regeneration
Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally. To…
New genetic screening method unlocks insights into human development
A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides new…
Frozen embryo transfers dominate assisted reproduction across Europe
More than 1.15 million assisted reproductive technology (ART) treatment cycles were reported across Europe in 2023, according to…
Smart prodrug targets Alzheimer’s disease using hydrogen peroxide signals
A substance that worsens dementia has become a “switch” that initiates treatment. KAIST researchers have developed a new…
Targeting a key protein reduces injury in steatotic liver transplantation
Background and aims Steatotic donor livers are highly susceptible to post-transplant dysfunction; however, the underlying mechanisms remain incompletely…
Kyoto University identifies a key regulator of insulin production
A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas…
Molecular map reveals how Down syndrome alters brain development
Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human…
Nanomedicine offers targeted solutions for breast cancer treatment
Breast cancer (BCA) is one of the most common cancers worldwide, with high mortality and morbidity in women.…