Wistar scientists develop new bispecific T cell engager to target ovarian cancer
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles
Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during…
Cold-exposed mothers pass metabolic protection to male rat offspring through milk
Cold exposure during early pregnancy altered breast milk bile acids and microbial metabolism, providing male rat offspring with…
Smart prodrug targets Alzheimer’s disease using hydrogen peroxide signals
A substance that worsens dementia has become a “switch” that initiates treatment. KAIST researchers have developed a new…
Single DNA injection provides long-lasting weight loss in mouse study
Scientists at The Wistar Institute have shown that a single injection of a small, circular piece of genetic…
Study identifies fPRDM16 as target for age-related pulmonary fibrosis
A study published recently in Current Molecular Pharmacology has uncovered a key mechanism linking aging to persistent pulmonary fibrosis, identifying…
Gene therapy successfully treats deadly childhood liver disease in mice
A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that…
New blood test tracks real time gene expression inside living brain tissue
Cell function is determined by how DNA is expressed into proteins. That process includes two main steps –…
Degrading mutant KRAS protein induces greater lung cancer regression
KRAS is one of the oncogenes most frequently altered in cancer, mutated in approximately one-third of lung adenocarcinomas.…
New thermal imaging system detects early melanoma before it is visible
Detecting melanoma before it becomes visible is a major challenge in dermatology. Now, with researchers from Université de…
Kyoto University identifies a key regulator of insulin production
A hallmark of Type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas…
Nanomedicine offers targeted solutions for breast cancer treatment
Breast cancer (BCA) is one of the most common cancers worldwide, with high mortality and morbidity in women.…