Chronic interferon exposure drives immunosuppression in tumors
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
Study identifies immune response causing severe COVID-19 susceptibility
Although the COVID-19 pandemic has largely subsided, scientists continue to investigate why the virus proved so deadly, causing…
Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment
A new study suggests that clearing symptom-driving nasal viruses could calm allergic inflammation and open a fresh treatment…
Neutrophils reduce the effectiveness of cancer immunotherapy in mice
A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less…
Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration
A major immune pathway once known for detecting DNA damage is now being linked to brain aging, glial…
Combination therapy improves response rates for chronic hepatitis B patients
Background and aims The optimal management strategy for adults with immune-tolerant (IT) chronic hepatitis B infection remains undefined.…
Study identifies antiviral protein IFN-γ as a potential biomarker for Long COVID fatigue
SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression.…
IFN-γ identified as alzheimer’s disease blood biomarker
A new study uncovers interferon gamma as both a powerful blood-based signal of Alzheimer’s disease (AD) and a…
Study reveals coffee triggers distinct cytokine responses compared with pure caffeine
A controlled human study reveals that coffee’s complex chemical matrix may shape immune responses differently than pure caffeine,…
Dynamic viral markers predict treatment response in hepatitis B
Background and aims The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in…
A single immune protein may help explain why kidney and heart disease often develop together
A growing body of human, genetic, and experimental evidence suggests that suPAR may not only signal disease risk…