Study uncovers how interferon-alpha treats rare blood cancers
The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem…
Chronic interferon exposure drives immunosuppression in tumors
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
Study identifies immune response causing severe COVID-19 susceptibility
Although the COVID-19 pandemic has largely subsided, scientists continue to investigate why the virus proved so deadly, causing…
Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment
A new study suggests that clearing symptom-driving nasal viruses could calm allergic inflammation and open a fresh treatment…
Neutrophils reduce the effectiveness of cancer immunotherapy in mice
A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less…
Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration
A major immune pathway once known for detecting DNA damage is now being linked to brain aging, glial…
Combination therapy improves response rates for chronic hepatitis B patients
Background and aims The optimal management strategy for adults with immune-tolerant (IT) chronic hepatitis B infection remains undefined.…
Study identifies antiviral protein IFN-γ as a potential biomarker for Long COVID fatigue
SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression.…
IFN-γ identified as alzheimer’s disease blood biomarker
A new study uncovers interferon gamma as both a powerful blood-based signal of Alzheimer’s disease (AD) and a…
Study reveals coffee triggers distinct cytokine responses compared with pure caffeine
A controlled human study reveals that coffee’s complex chemical matrix may shape immune responses differently than pure caffeine,…
Dynamic viral markers predict treatment response in hepatitis B
Background and aims The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in…