Aging brain actively shapes biology and progression of tumors
Brain tumors develop within an organ that changes substantially with age. A new review in Ageing and Cancer…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
Scientists discover molecular mechanism behind anesthesia-induced unconsciousness
Researchers at Weill Cornell Medicine and Birkbeck, University of London, have identified a site where a commonly used…
Amsterdam UMC researchers overturn long-standing biological pacemaker dogma
Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field. In a new preclinical…
Researchers identify genetic cause of severe childhood lung disease
A new report in the American Journal of Human Genetics describes a novel disorder caused by biallelic loss-of-function variants in…
Scientists mimic heart cell signaling using organic conductive plastics
For the first time, scientists have succeeded in artificially mimicking the ion signaling of heart muscle cells. To…
Researchers discover water’s role in brain learning and memory signaling
How do we learn to remember? At the most fundamental level, it’s all about chemicals and electricity. Beyond…
The molecular mechanism that turns cool temps into nerve signals
When you reach into a bucket of ice, open your front door on a snowy day, or feel…
New review reveals complex polygenic architecture underlying common epilepsies
An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common…
Understanding PIEZO2 mutations and sensory disorders
Every time we feel a gentle tap on the skin, specialized nerve cells convert that physical force into…
Ion channel TRPV4 found to regulate relief after scratching an itch
When you scratch an itch, something tells your brain when to stop. That moment of relief, when scratching…
New research identifies faulty TRPM3 ion channel in ME/CFS immune cells
A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), providing long-awaited…