Targeting metabolic pathways could prevent relapse in KRAS-mutant cancers
Our cells rely on tightly regulated signaling pathways to control when they grow, divide, and survive. When these…
Duke researchers discover molecules that target vital cell signaling proteins
To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive…
Early diabetes drug treatment links to better survival after diagnosis thresholds
New Korean health-screening data suggest prompt antidiabetic treatment after type 2 diabetes thresholds are crossed may improve survival,…
Melatonin improves skin flap survival by reducing ferroptosis
Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries…
Engineered CAR-T cells offer potential rheumatoid arthritis cure
For the 18 million people living with rheumatoid arthritis, disease management currently means a lifetime of injections-a reality…
Synthetic gut communities reveal how diet rewires the microbiome
By simplifying the gut’s microbial complexity, synthetic communities could help scientists pinpoint how specific foods influence microbial function,…
New spatial map reveals treatment vulnerabilities in bladder cancer
Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder…
Oropouche virus infected millions more than official data shows
The recent Oropouche virus outbreak in 2023 drew attention in Brazil and other Latin American countries not only…
New CellTrap technology reveals how single immune cells attack brain tumors
Established laboratory tests mainly capture average values across many cells and show, for example, how many cancer cells…
Synthetic biology platform unmasks hidden bacterial targets of bacteriophages
An interdisciplinary team of Rice University researchers has uncovered previously unknown relationships between bacteriophages – viruses that infect…
Heart tissue repair drug may also help repair and regenerate damaged kidney tissues
A drug previously developed at UCLA to help heart tissue repair itself after a heart attack might also…
Engineered blood clots form faster to stop severe bleeding
Blood clotting is one of the body’s oldest survival mechanisms-a biological defense that has protected humans from dangerous…