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Browsing Tag

Life Sciences

178 posts
BBusiness
Computational investigation of the sequence context of arginine/glycine-rich motifs in the human proteome | BMC Genomics
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Computational investigation of the sequence context of arginine/glycine-rich motifs in the human proteome | BMC Genomics

  • October 6, 2025
Human RG motif statistical comparisons reveal significant differences in physicochemical properties To understand important characteristics or properties of…
GGenetics
CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold
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CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold

  • October 6, 2025
Input embeddings In CellNavi, we use single-cell raw count matrices as the only input. Specifically, the single-cell sequencing…
GGenetics
Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics
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Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics

  • October 3, 2025
Preparation of preliminary data In all samples, the proportion of clean reads was higher than 99.5% (Table S2),…
SScience
Deciphering the origins of guanylate-binding proteins in mammals (Monotreme, Marsupials and Placentals) | BMC Biology
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Deciphering the origins of guanylate-binding proteins in mammals (Monotreme, Marsupials and Placentals) | BMC Biology

  • October 1, 2025
Guanylate-binding proteins have important roles in immunity, being involved in the cell-autonomous innate immune response against bacterial, parasitic…
BBusiness
Targeting RNA with small molecules using state-of-the-art methods provides highly predictive affinities of riboswitch inhibitors
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Targeting RNA with small molecules using state-of-the-art methods provides highly predictive affinities of riboswitch inhibitors

  • October 1, 2025
Harries, L. W. RNA biology provides new therapeutic targets for human disease. Front. Genet. 10, 205 (2019). CAS …
BBusiness
A closed-loop method for precise genome size estimation using HiFi reads | BMC Genomics
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A closed-loop method for precise genome size estimation using HiFi reads | BMC Genomics

  • September 29, 2025
Blommaert J. Genome size evolution: towards new model systems for old questions. Proc Biol Sci. 2020;287(1933): 20201441. PubMed …
SScience
Chromosome-level genome assembly for Sichuan taimen (Hucho bleekeri) reveals the extraordinary tandem repeat proportions and its persistent population shrinkage | BMC Genomics
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Chromosome-level genome assembly for Sichuan taimen (Hucho bleekeri) reveals the extraordinary tandem repeat proportions and its persistent population shrinkage | BMC Genomics

  • September 26, 2025
Wang K, Zhang SH, Wang DQ, Wu JM, Wang CY, Wei QW. Conservation genetics assessment and phylogenetic relationships…
BBusiness
Automated environmental metagenomics using Oxford nanopore sequencing | BMC Genomics
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Automated environmental metagenomics using Oxford nanopore sequencing | BMC Genomics

  • September 26, 2025
Sereika M, Kirkegaard RH, Karst SM, Michaelsen TY, Sørensen EA, Wollenberg RD, et al. Oxford nanopore R10.4 long-read…
SScience
Non-muscle myosin II-dependent cumulus cell migration at ovulation is required for sperm to reach the egg in mice
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Non-muscle myosin II-dependent cumulus cell migration at ovulation is required for sperm to reach the egg in mice

  • September 24, 2025
We began by collecting COCs from large antral follicles of eCG-primed mice and incubating them in medium supplemented…
BBusiness
MaskMol: knowledge-guided molecular image pre-training framework for activity cliffs with pixel masking | BMC Biology
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MaskMol: knowledge-guided molecular image pre-training framework for activity cliffs with pixel masking | BMC Biology

  • September 24, 2025
Fleming N. How artificial intelligence is changing drug discovery. Nature. 2018;557(7706):S55–S55. CAS  PubMed  Google Scholar  Zeng X, Wang…
CComputing
Marketers using agentic AI foresee quantum computing’s rise soon
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Marketers using agentic AI foresee quantum computing’s rise soon

  • September 24, 2025
New research indicates that nearly one in three marketers already using agentic AI anticipate quantum computing will impact…
BBusiness
Merck KGaA & Siemens Deepen Partnership to Accelerate AI Drug Discovery & Development
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Merck KGaA & Siemens Deepen Partnership to Accelerate AI Drug Discovery & Development

  • September 23, 2025
About the Life Science business of Merck KGaA, Darmstadt, Germany The Life Science business of Merck KGaA, Darmstadt,…
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