A pathogenic mutation in α-SNAP impairs membrane lipid binding by concealing a critical hydrophobic loop
Barnard, R. J., Morgan, A. & Burgoyne, R. D. Stimulation of NSF ATPase activity by alpha-SNAP is required…
haCCA: multi-module Integration of spot-based spatial transcriptomes and metabolomes
Vandereyken, K. et al. Methods and applications for single-cell and spatial multi-omics. Nat. Rev. Genet. 24, 494–515 (2023).…
Projected human land-use pressures and natural habitat conversion risk within global terrestrial protected areas
Protected Planet Report 2020 (UNEP-WCMC and IUCN, 2021). Pringle, R. M. Upgrading protected areas to conserve wild biodiversity.…
Soil biodiversity effects on ecosystems
Anthony, M. A., Bender, S. F. & Van Der Heijden, M. G. A. Enumerating soil biodiversity. Proc. Natl…
Five rules for scientifically credible nature markets
UNEP. State of Finance for Nature 2023 (UNEP, 2023). Kedward, K., zu Ermgassen, S. O. S. E., Ryan-Collins,…
Fungal commensal promotes intestinal repair via its secreted peptide in mice
Barker, N. Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration. Nat. Rev. Mol. Cell Biol.…
Large-scale testing of antimicrobial lethality at single-cell resolution predicts mycobacterial infection outcomes
Sample collection We used the Mycobacterium abscessus laboratory strain ATCC-19977, the avirulent Mycobacterium tuberculosis strain H37Ra and the…
Ecological processes shaping Antarctic terrestrial biodiversity change
Lee, J. R. et al. Climate change drives expansion of Antarctic ice-free habitat. Nature 547, 49–54 (2017). Article …
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
Sebé-Pedrós, A. et al. The dynamic regulatory genome of capsaspora and the origin of animal multicellularity. Cell 165,…
Opinion: America’s new vaccine doctrine for children replaces data with dogma
Outside the BoxThe Trump administration has dropped recommendations for six vaccines and one preventative therapy for all children…
L-cystine alleviates necrotizing enterocolitis by regulating ferroptosis and Th17 cell differentiation via the IL-6/STAT3 pathway
Roberts, A. G., Younge, N. & Greenberg, R. G. Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and…
Transcriptomic decoding of regional cortical vulnerability to drug-resistant epilepsy using 7T MRI
Fiest, K. M. et al. Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies.…